Diseases / conditions / health problems studied

Drug evaluations:

  • A gastro-intestinal disorder (three drugs)
  • Breast cancer (tamoxifen vs. toremifen)
  • Chronic obstructive lung disease (COPD)
  • Depression (fluoxetine vs. moclobemide, fluoxetine vs. dothiepine)
  • Drug eluting stents vs. bare metal stents
  • Early rheumatoid arthritis (single drug treatment vs. 4-drug combination)
  • Erectial dysfunction
  • Hormone replacement therapy in healthy postmenopausal women
  • MS disease (interferon vs. not)
  • Mycosis in mouth
  • Osteoporosis (alendronate)
  • Parkinson’s disease
  • Psoriasis
  • Schizophrenia
  • Restenosis prevention after PTCA
  • Seasonal affective disorder (fluoxetine vs. moclobemide)

Surgery:

  • Accident-caused infuries in wrist, finger, elbow, clavicle and Achilles tendon
  • Acromioplasty
  • Adolescent idiopathic scoliosis (Harrington instrumentation)
  • Anterior cervical decompression
  • Atrial correction of the transposition of the great arteries
  • Bladder cancer
  • Blood vessel surgery
  • Brain tumor
  • Breast cancer and reconstruction
  • Breast reduction
  • Cataract
  • Cervical and lumbar patients with spinal nerve root compression
  • Cholelithiasis
  • Cochlear implant
  • Coronary artery disease (CABG, re-CABG, PTCA, conservative treatment).
  • Epicondylitis (Topaz microtenotomy in lateral...)
  • Epilepsy (surgery vs. no surgery).
  • Esophageal cancer (surgery vs. palliative)
  • Face injuries (mandible, zygoma, orbit)Knee and hip replacements
  • Gastrectomy for gastric carcinoma
  • Gastric bypass surgery
  • Gastrointestinal surgery
  • Hallux valgus (surgery vs. orthosis vs. watchful waiting)
  • Hernia
  • Herniated lumbar disc (surgery vs. conservative treatment)
  • Hip fracture
  • Hysterectomy
  • Incontinence (surgery vs. physiotherapy)
  • Intermittent claudication
  • Laparoscopic cholecystectomy
  • Liver transplantation
  • Lumbar spinal stenosis (surgery vs. conservative treatment)
  • Lung cancer
  • Microdiscectomy for lumbar disc herniation
  • Neurosurgery (several diagnoses)
  • Obesity (sleeve vs. bypass)
  • Pancreatic resections
  • Pneumonectomy
  • Pituitary adenoma
  • Primary brain tumor surgery
  • Prostata hyperplasia
  • Prostate cancer
  • Renal cancer
  • Renal transplantation
  • Macroreplantation of lower limb
  • Ruptured cerebral aneurysm
  • Severe obesity
  • Silicon breast implants
  • Snoring
  • Varicose veins
  • Vecchietti procedure
  • Venous leg ulcers (surgery vs. compression)

Rehabilitation:

  • Cognitive training (through a website)
  • Coronary artery disease (CAD) patients (rehabilitation)
  • Developmental language disorder
  • Employed people with reduced ability to work (vocationally oriented medical rehabilitation)
  • Geriatric rehabilitation (n=741, aged 65+)
  • Hip fracture (three approaches to rehabilitation)
  • Holistic geriatric assessment, treatment and rehabilitation (n=1500, aged 75+)
  • Inspiration activity of the elderly
  • Lumbar disc herniation (muscle exercise program after surgery)
  • MS patients (inpatient rehabilitation)
  • Muscular strength training of the elderly
  • Orthopaedic patients (rehabilitation)
  • Peripheral artery disease (physical rehabilitation)
  • Physiotherapy
  • Primary total knee arthoroplasty (multidisciplinary rehabilitation)
  • Rehabilitation councelling of the elderly
  • Resistance training
  • Speech rehabilitation
  • Stroke (treatment, intensive vs. conventional rehabilitation).
  • Sub-acute low back pain (early activation and rehabilitation)
  • Visual impairment (rehabilitation)

Other conditions/treatments

  • Acoustic neurinoma
  • Acromegaly
  • Acute low back pain
  • ADHD
  • Alcohol consumption
  • Alexithymia
  • Alzheiner's disease
  • Anaemic patients with solid and haematological tumours
  • Aneurysma (celebral haemorrhage)
  • Aphasia
  • Arteriosclerotic disease (a multi-component intervention to prevent complications)
  • Asthma (intensive vs. conventional patient education and supervision for self-management)
  • Atopic eczema
  • Atrial fibrillation
  • Back pain in pregnant women (back supporting vest vs. conventional approach to treating back pain)
  • Basedow’s disease
  • Bipolar affective disorder
  • Burn injury
  • Cancer of thyroid gland
  • Cancer of urinary bladder
  • Chronic non-malignant pain (medical management)
  • Diabetes (gestational)
  • Diabetes (prevention of type 2; type 1 and 2 patients with different complications)
  • Diastrophic dysplasia
  • Dizziness with migraine as an etiological factor
  • Drug abuse and addiction (treatment)
  • Duchenne-Erb paresis
  • Eating disorders
  • Effects of smoking
  • Epidemic nephropathy
  • Esophagus atresia
  • ESRD and dialysis
  • Fabry’s disease
  • FH
  • Fibromyalgia
  • Forearm fracture
  • Glaucoma
  • Gonarthritis
  • Hearing problems
  • HIV/AIDS
  • Human papilloma virus (HPV)
  • Hypertension
  • Hyperthyreosis
  • Inflammatory bowel disease (Crohn's disease, ulcerative colitis)
  • “Intelligent bracelet” for dementing elderly
  • Irritable bowel syndrome
  • Kallmann's syndrome
  • Malnutrition
  • Mayer Rokitansky Küster Hauser Syndrome (vaginal aplasia)
  • Melanoma
  • Metabolic syndrome
  • Multiple myeloma
  • Myocardial infarction
  • Nephrolith
  • Non-specific back pain
  • Oral health
  • Osteoarthritis
  • Pancreatic cancer (IMRI-guided neurolytic celiac plexus block in pancreatic cancer pain)
  • Pancreatic exocrine insufficiency
  • Patients coming to angiography
  • Preterm birth (effect on HRQoL in adulthood)
  • Prostate cancer (screening and treatment)
  • Prostatic hyperplasia
  • Psychiatric disorders (major depressive disorder, dysthymia, alcohol dependence, agoraphobia, generalized anxiety disorder, panic disorder, social phobia)
  • Psychosis
  • Rhinoconjunctivitis
  • Renal cancer
  • Sciatica
  • Severe chronic pain (spinal cord stimulator)
  • Severe obesity (combined VLCD and behaviour modification)
  • Sleep apnea
  • Sparm of celebral arteries
  • Spinal cord injury
  • Teleultrasound examination
  • Tinnitus
  • Trigeminus neuralgia
  • Weaning from smoking

Other projects:

  • The Finnish National Health Survey 1995/96
  • Health2000 survey in Finland (a random sample of 6329 of adult population aged 30+)
  • The Danish National Health Survey 2000.
  • Experiment on feasibility and usefulness of measuring HRQoL of patients before and after treatment routinely in the hospitals of Helsinki and Uusimaa Hospital District (n≈12000, in 10 specialties, over 30 diagnoses)
  • Experiment on including the 15D as a standard part of anamnesis in electronic medical records (Turku University Hospital)
  • DEBATE-study (Drugs and Evidence-Based Medicine in the Elderly) (n=400, aged 75+ with cardiovascular diseases)
  • Elderly in Helsinki, Finland vs. in Tallinn, Estonia
  • DELI-study (elderly inpatients with delirium, n=174)
  • BIFIDO-study (aged in old people's homes and nursing homes, n=209)
  • The process of frailty and disability in older women (The Finnish Twin Study on Ageing, FITSA).
  • HRQoL of young military conscripts (15D vs. Rand-36)
  • Prevention of gestational diabetes
  • HRQoL of long-term care patients